Go beyond cell lines to uncover dynamic tumor microenvironment
This DDW 2025 poster showcases the development of patient-derived organoids and immune cell co-cultures using colorectal (CRC) and non-small cell lung cancer (NSCLC) patient tumors and various immune cell types, such as T cells, PBMCs, or macrophages.
Our validated multi-module screening readouts, including imaging-based cell viability, flow cytometry, and cytokine secretion reveal new opportunities to assess immunotherapy activity and toxicity in autologous or allogeneic settings.
What you'll learn:
- How we isolate and expand epithelial, lymphoid, and stromal cell types to reconstitute the tumor microenvironment
- How co-cultures with TILs and BiTEs reveal tumor-specific reactivity, including cytokine secretion and cell killing
- How to evaluate safety and efficacy of myeloid-targeting antibodies using image-based and cytokine readouts
Discover a better way to model the tumor microenvironment
Test your immunotherapy in a co-culture platform that captures real patient biology
