---
title: Organoid co-cultures with autologous T cells to assess toxicity and efficacy of bispecific antibodies
description: Discover our poster on organoid co-cultures with autologous T cells to assess the toxicity and efficacy of bispecific antibodies that we presented at IO Summit Boston
image: https://resources.huborganoids.nl/hubfs/io-summit22-poster-organoid-co-coltures.jpg
---

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Presented in AACR 2023

# Organoid co-cultures with autologous T cells to assess toxicity and efficacy of bispecific antibodies

![ELRIG 2022 Poster](https://resources.huborganoids.nl/hs-fs/hubfs/Assets%202022/elrig-poster-2022-bispecific-antibodies.png?width=300&name=elrig-poster-2022-bispecific-antibodies.png)

Immunotherapies have demonstrated great success in clinical treatment for certain types of cancer. However, the lack of preclinical models that preserve patient-specific tumor antigen expression and recapitulate the immune cell response to tumors *in vivo* is hindering the successful development of novel therapeutic strategies.

#### Download this poster to discover:

- The establishment of a non-small cell lung cancer (NSCLC) organoid and tumor-infiltrating lymphocyte (TIL) co-culture platform
- The available readouts that provide an indication of T-cell bispecific (TCB) activity
- The potential of NSCLC organoid-TIL co-culture platform in assessing the toxicity and efficacy of bispecific antibodies targeting tumor antigens.

### Download our poster

![Logo HUB Organoids](https://resources.huborganoids.nl/hubfs/raw_assets/public/HUBOrganoids_May2021/images/logo-huborganoids-white.svg "Logo HUB Organoids")

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