Patient-Derived Organoids: A New Frontier in ADC Development
See how PDOs are accelerating ADC development and explore real-world case studies where our insights guided key preclinical development decisions
See why biotech innovators are choosing organoid technology
Why choose Organoid Technology for your ADC program?
Traditional ADC models like 2D cell lines and PDXs often fail to predict clinical outcomes, leading to high attrition and dose-limiting toxicities. Patient-derived organoids (PDOs) provide a more predictive alternative. These 3D tumor models preserve patient-specific architecture and genetics, enabling accurate assessment of ADC efficacy and off-target toxicities across both tumor and healthy tissues.
What you'll learn:
- How patient-derived organoids (PDOs) outperform traditional cell lines and PDX models in ADC development
- Data showcasing how HUB Organoids capture the diversity of patient responses
- An overview of our comprehensive ADC services portfolio
- Two in-depth case studies illustrating how we’ve helped clients make confident, data-driven preclinical decisions
Discover our ADC development solutions
Whether you need to assess antigen expression in patient-derived models, evaluate ADC potency and off-target toxicities, or run basket screens across multiple cancer indications, our tailored service packages are designed to accelerate your program.

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