---
title: "Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response"
description: "Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response"
image: https://resources.huborganoids.nl/hubfs/SocialMedia-publication-organoids-as-a-biomarker-1200x1200.jpg
---

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# Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response

J Exp Clin Cancer Res | 2024 Feb

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## Abstract

The inability to predict treatment response of colorectal cancer patients results in unnecessary toxicity, decreased efficacy and survival. Response testing on patient-derived organoids (PDOs) is a promising biomarker for treatment efficacy. This study aims to optimize PDO drug screening methods for correlation with patient response and explore the potential to predict responses to standard chemotherapies.

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